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SB 206553
CAS No. 1197334-04-5
SB 206553 ( SB206553 )
产品货号. M10703 CAS No. 1197334-04-5
SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥8667 | 有现货 |
|
| 50MG | ￥17658 | 有现货 |
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| 100MG | ￥22680 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SB 206553
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes.
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产品描述SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes; exhibits anxiolytic-like properties both in vitro and in vivo.Anxiety Discontinued
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同义词SB206553
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域Neurological Disease
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适应症Anxiety
化学信息
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CAS Number1197334-04-5
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分子量328.80
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分子式C17H16N4O.HCl
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(N1C(C(CC1)=C2)=CC3=C2N(C)C=C3)NC4=CC=CN=C4.[H]Cl
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化学全称3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Forbes IT, et al. J Med Chem. 1995 Jul 7;38(14):2524-30.
2. Upton N, et al. Eur J Pharmacol. 1998 Oct 16;359(1):33-40.
3. Kennett GA, et al. Br J Pharmacol. 1996 Feb;117(3):427-434.
4. Porras G, et al. Neuropsychopharmacology. 2002 Mar;26(3):311-24.
2. Upton N, et al. Eur J Pharmacol. 1998 Oct 16;359(1):33-40.
3. Kennett GA, et al. Br J Pharmacol. 1996 Feb;117(3):427-434.
4. Porras G, et al. Neuropsychopharmacology. 2002 Mar;26(3):311-24.
产品手册
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